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      <qbo:mapNotes xmlns:qbo="https://dr-richard-barker.github.io/quantum-biology-atlas/qbo/1.0">Iron uptake and sulfate assimilation. One of two maps the review motivates but does not draw. That is an odd gap, because mineral nutrition is where the direct Arabidopsis near-null-field evidence is strongest: three separate studies report effects on root mineral nutrition, iron uptake efficiency and Fe-S interplay. The map makes the loop visible. Sulfate assimilation supplies the sulfide that every cluster on QBM-04 is built from, and sulfite reductase is itself a ferredoxin-dependent siroheme-[4Fe-4S] enzyme drawing on plastid reducing power from QBM-02 — so iron and sulfur status are not two inputs but one feedback system, which is exactly why Vigani et al. found the effect most pronounced under combined Fe and S deficiency. Note the tier pattern: uptake and assimilation are T2 on real evidence, but they are classed as structural context because no quantum route is proposed for them. A demonstrated effect with no mechanism is recorded here as precisely that. Derived from: Motivated by section 6 and the Islam 2020 / Vigani 2021 / Narayana 2018 evidence in Porterfield &amp; Barker, "Plant Responses to Near-Null Magnetic Fields" — no corresponding figure exists in the manuscript</qbo:mapNotes>
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        <label text="the NNMF evidence sits here" />
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        <qbo:annotation xmlns:qbo="https://dr-richard-barker.github.io/quantum-biology-atlas/qbo/1.0" entity="QBO:FE_SUPPLY" evidenceTier="T2" confidence="verified">
          <qbo:quantumClass>structural_context</qbo:quantumClass>
          <qbo:xref db="chebi">CHEBI:29033</qbo:xref>
          <qbo:xref db="chebi">CHEBI:29034</qbo:xref>
          <qbo:xref db="chebi">CHEBI:16189</qbo:xref>
          <qbo:evidence ref="Islam2020" doi="10.3389/fpls.2020.00325" direction="decrease" fieldRegime="NNMF">The geomagnetic field contributes to efficient iron uptake in Arabidopsis; reducing it to near-null affects root metal reductase activity.
</qbo:evidence>
          <qbo:evidence ref="Vigani2021" doi="10.3390/ijms221810166" direction="altered" fieldRegime="NNMF">Geomagnetic-field-dependent modulation of iron-sulfur interplay in Arabidopsis, most pronounced under combined Fe and S deficiency.
</qbo:evidence>
          <qbo:evidence ref="Narayana2018" doi="10.1016/j.lssr.2018.08.005" direction="altered" fieldRegime="NNMF">Reduction of the geomagnetic field to near-null affects Arabidopsis root mineral nutrition.
</qbo:evidence>
          <qbo:rationale>Note carefully what the cited work does and does not show. Islam 2020 and Vigani 2021 measured iron uptake and Fe-S interplay under altered field conditions — nutritional physiology. Neither measured cluster assembly. This entity is T2 because the field effect is demonstrated for the process it names; the assembly entities above remain T3 because that evidence does not reach them.
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        <label text="reductase activity ↓ under NNMF" />
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          <qbo:evidence ref="Islam2020" doi="10.3389/fpls.2020.00325" direction="decrease" fieldRegime="NNMF">The geomagnetic field contributes to efficient iron uptake in Arabidopsis; near-null conditions affect root metal reductase activity.
</qbo:evidence>
          <qbo:evidence ref="Narayana2018" doi="10.1016/j.lssr.2018.08.005" direction="altered" fieldRegime="NNMF">Near-null magnetic field conditions affect Arabidopsis root mineral nutrition.
</qbo:evidence>
          <qbo:rationale>Carries demonstrated near-null-field evidence and NO proposed quantum route, and is classed structural_context to say so. Islam et al. measured reduced root metal reductase activity under field reduction — a real, reproducible effect with no mechanism attached. FRO2 is a flavocytochrome with FAD and two hemes, so a spin route could be argued; the review does not argue it, and no measurement supports it, so it is not claimed here.
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          <qbo:quantumClass>iron_sulfur_4Fe4S</qbo:quantumClass>
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          <qbo:evidence ref="Vigani2021" doi="10.3390/ijms221810166" direction="altered" fieldRegime="NNMF">Field conditions modulate Fe-S interplay in Arabidopsis, most strongly under combined iron and sulfur deficiency.
</qbo:evidence>
          <qbo:rationale>Sulfite reductase carries a siroheme-[4Fe-4S] cofactor and is ferredoxin- dependent, so this pathway both consumes plastid reducing power and contains an Fe/S centre. It also supplies the sulfide that every cluster on QBM-04 is built from — a genuine feedback loop rather than a linear dependency.
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        <label text="ferritin, NA, NRAMP" />
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          <qbo:quantumClass>structural_context</qbo:quantumClass>
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        <label text="S donor for assembly" />
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          <qbo:quantumClass>structural_context</qbo:quantumClass>
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          <qbo:quantumClass>structural_context</qbo:quantumClass>
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      <extension>
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          <qbo:quantumClass>iron_sulfur_2Fe2S</qbo:quantumClass>
          <qbo:nucleus>57Fe</qbo:nucleus>
          <qbo:nucleus>33S</qbo:nucleus>
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          <qbo:rationale>Holds a transient, solvent-exposed [2Fe-2S] cluster whose assembly involves iron redox chemistry and sulfide transfer. A nascent cluster on a scaffold is more exposed and shorter-lived than a mature one buried in a protein, which makes it a more credible point of perturbation than the finished product.
</qbo:rationale>
          <qbo:caveat>Entirely untested. No experiment has measured scaffold occupancy or transfer rate under any magnetic field condition.
</qbo:caveat>
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        <qbo:annotation xmlns:qbo="https://dr-richard-barker.github.io/quantum-biology-atlas/qbo/1.0" entity="QBO:SUF_SYSTEM" evidenceTier="T3" confidence="inferred">
          <qbo:quantumClass>iron_sulfur_4Fe4S</qbo:quantumClass>
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          <qbo:rationale>Builds every cluster in the chloroplast, including PSI's FX/FA/FB and ferredoxin's [2Fe-2S]. It is the single upstream dependency of QBM-02's strongest nodes.
</qbo:rationale>
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        <label text="respiration" />
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        <label text="photosynthesis" />
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        <label text="DNA replication" />
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        <qbo:annotation xmlns:qbo="https://dr-richard-barker.github.io/quantum-biology-atlas/qbo/1.0" entity="QBO:FES_CLIENTS" evidenceTier="T3" confidence="inferred">
          <qbo:quantumClass>iron_sulfur_4Fe4S</qbo:quantumClass>
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          <qbo:nucleus>57Fe</qbo:nucleus>
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          <qbo:rationale>Collected here so the map can show, in one edge, that a single assembly defect reaches respiration, photosynthesis, the TCA cycle, nitrogen and sulfur assimilation and DNA replication simultaneously. That breadth is the review's argument for why Fe/S biology deserves attention ahead of cryptochrome.
</qbo:rationale>
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        <label text="closes the loop" />
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        <qbo:annotation xmlns:qbo="https://dr-richard-barker.github.io/quantum-biology-atlas/qbo/1.0" entity="QBO:FERREDOXIN" evidenceTier="T2" confidence="reported">
          <qbo:quantumClass>iron_sulfur_2Fe2S</qbo:quantumClass>
          <qbo:nucleus>57Fe</qbo:nucleus>
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          <qbo:xref db="agi">AT1G10960</qbo:xref>
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          <qbo:xref db="go_component">GO:0009570</qbo:xref>
          <qbo:evidence ref="Vigani2021" doi="10.3390/ijms221810166" direction="altered" fieldRegime="NNMF">Geomagnetic field conditions modulate iron-sulfur interplay in Arabidopsis, particularly under combined iron and sulfur deficiency.
</qbo:evidence>
          <qbo:rationale>The distribution hub of plastid reducing power. A perturbation here reaches carbon fixation, nitrogen and sulfur assimilation and redox regulation at once, which is why the review nominates ferredoxin biogenesis specifically.
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